⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606190 | 0.79 | — | — | |
| SCHEMBL21728783 | 0.77 | — | — | |
| SCHEMBL15795937 | 0.75 | — | — | |
| SCHEMBL542297 | 0.75 | ALDH1A1 (0.37) | — | |
| SCHEMBL542299 | 0.75 | ALDH1A1 (0.37) | — | |
| SCHEMBL23221248 | 0.75 | — | — | |
| SCHEMBL3058544 | 0.73 | — | — | |
| SCHEMBL23081624 | 0.73 | MAOA (0.39) | — | |
| SCHEMBL11926269 | 0.73 | GAA (0.41) | — | |
| SCHEMBL2423255 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2988597-B1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | HARVARD COLLEGE (US) | 2022-06-08 | — | — | EP | disclosed |
| US-10712353-B2 | Antibodies to olanzapine haptens and use thereof | JANSSEN PHARMACEUTICA NV (BE) | 2020-07-14 | — | — | US | disclosed |
| WO-2020068689-A1 | TERPINOID DERIVATIVES AND USES THEREOF | FRONTHERA U.S. PHARMACEUTICALS LLC (US) | 2020-04-02 | — | — | WO | disclosed |
| EP-3082877-B1 | CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2019-08-28 | — | — | EP | disclosed |
| WO-2019145245-A1 | HERBICIDALLY ACTIVE 3-PHENYLISOXAZOLINE-5-CARBOXAMIDES OF CYCLOPENTENYL CARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-08-01 | — | — | WO | disclosed |
| EP-2922575-B1 | TRIOXACARCINS, TRIOXACARCIN-ANTIBODY CONJUGATES, AND USES THEREOF | HARVARD COLLEGE (US) | 2019-06-26 | — | — | EP | disclosed |
| EP-2688891-B1 | BENZOXAZEPIN COMPOUNDS SELECTIVE FOR PI3K P110 DELTA AND METHODS OF USE | HOFFMANN LA ROCHE (CH) | 2017-11-15 | — | — | EP | disclosed |
| EP-2688891-B1 | BENZOXAZEPIN COMPOUNDS SELECTIVE FOR PI3K P110 DELTA AND METHODS OF USE | HOFFMANN LA ROCHE (CH) | 2017-11-15 | — | — | EP | disclosed |
| US-9758522-B2 | Hydrophobically tagged small molecules as inducers of protein degradation | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| EP-3087058-B1 | PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF PYRAZOLES | ISAGRO SPA (IT) | 2017-09-06 | — | — | EP | disclosed |
| US-20070142380-A1 | Viral Polymerase Inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | US | disclosed |
| US-7223785-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-29 | — | — | US | disclosed |
| US-6600071-B2 | Starting materials or intermediates and the cyclization of these under suitable reaction conditions to give compounds of the formula I. The intermediates of the formula II are novel. for argrochemicals | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-29 | — | — | US | disclosed |
| US-20030109717-A1 | Preparation of substituted hydroxypyrazoles | GOTZ NORBERT (DE) | 2003-06-12 | — | — | US | disclosed |
| US-6472538-B1 | HIGH YIELD COUPLING, HYDROGENATION AND CYCLIZATION TO FORM CHEMICAL INTERMEDIATES FOR HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |
| EP-1127050-A1 | METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000027821-A1 | METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-18 | — | — | WO | disclosed |
| US-5948780-A | ADMINISTERING A METALLOPROTEINASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-09-07 | — | — | US | disclosed |
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |
| US-3965174-A | HYDROGENATION CATALYST | UNIROYAL, INC. (US) | 1976-06-22 | — | — | US | disclosed |