Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.78 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.78 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188216 | 0.93 | CHRNB2 (0.67) | CHRNB2CHRNA4GAAEPHX2CYP1A2 | |
| SCHEMBL7411609 | 0.88 | CHRNB2 (1.00) | CHRNB2CHRNA4DRD2DRD3LTA4H | |
| SCHEMBL30601974 | 0.85 | CHRNB2 (0.57) | CHRNB2CHRNA4NPC1RAB9ACYP1A2 | |
| SCHEMBL6452945 | 0.82 | NPC1 (0.79) | NPC1RAB9ACYP1A2LTA4HCA12 | |
| Hydrochloric Acid SCHEMBL7013705 | 0.81 | NPC1 (0.82) | NPC1RAB9ALTA4HKDM4E | |
| SCHEMBL14204567 | 0.81 | NPC1 (0.77) | NPC1RAB9ALTA4HCA12CA1 | |
| SCHEMBL14578276 | 0.80 | ALDH1A1 (0.69) | NPC1RAB9ALTA4HKDM4EALDH1A1 | |
| SCHEMBL20037920 | 0.79 | NPC1 (0.60) | GAANPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL30422251 | 0.77 | GAA (0.52) | CHRNB2CHRNA4GAANPC1RAB9A | |
| SCHEMBL3577214 | 0.77 | TSHR (0.55) | CHRNB2CHRNA4NPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119317622-A | Compounds useful as TYK2 inhibitors, preparation method and application thereof in medicine | 上海致根医药科技有限公司 | 2025-01-14 | — | — | CN | disclosed |
| WO-2023165574-A1 | COMPOUND USED AS TYK2 INHIBITOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 上海致根医药科技有限公司 | 2023-09-07 | — | — | WO | disclosed |
| CN-116693449-A | Compounds useful as TYK2 inhibitors, preparation method and application thereof in medicine | 上海致根医药科技有限公司 | 2023-09-05 | — | — | CN | disclosed |