Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | SMO | Q99835 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LCLAT1 | Q6UWP7 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24473977 | 1.00 | TSHR (0.64) | TSHRNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL26078553 | 0.86 | ALDH1A1 (0.64) | TSHRNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL736261 | 0.83 | LMNA (0.62) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30587152 | 0.83 | ALDH1A1 (0.60) | TSHRNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL24473982 | 0.83 | ALDH1A1 (0.60) | TSHRNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL24474001 | 0.82 | SMN1; SMN2 (0.67) | TSHRNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL24474019 | 0.81 | KDM4E (0.74) | TSHRNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL8770855 | 0.80 | NPC1 (0.74) | TSHRNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL24473983 | 0.79 | NPC1 (0.61) | TSHRNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL30587155 | 0.79 | NPC1 (0.61) | TSHRNPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457353-A | N-substituted 4- (5-phenyl-1, 3, 4-oxadiazol-2-yl) anilines for the treatment and prophylaxis of hepatitis b virus infections | 豪夫迈·罗氏有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-116457353-A | N-substituted 4- (5-phenyl-1, 3, 4-oxadiazol-2-yl) anilines for the treatment and prophylaxis of hepatitis b virus infections | 豪夫迈·罗氏有限公司 | 2023-07-18 | — | — | CN | disclosed |