SCHEMBL3058780

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3058213	0.87	CHRM1 (0.44)	CHRM1CHRM3CHRM2KCNQ4KCNQ5
	SCHEMBL4738206	0.83	CHRM2 (0.46)	CHRM1CHRM3CHRM2ALDH1A1MLNR
	SCHEMBL3049232	0.81	CHRM1 (0.43)	CHRM1CHRM3CHRM2KDM1AHDAC8
	SCHEMBL18721166	0.80	KCNQ4 (0.43)	CHRM1CHRM3CHRM2KDM1AHDAC8
	SCHEMBL3063916	0.80	KCNQ4 (0.43)	CHRM1CHRM3CHRM2KDM1AHDAC8
	SCHEMBL18721167	0.76	NR1D1 (0.47)	ALDH1A1CYP3A4NPC1MAPTRAB9A
	SCHEMBL31205987	0.74	KDM1A (0.49)	KDM1AALDH1A1MAPK1HTTNPC1
	SCHEMBL2527066	0.74	MCHR1 (0.45)	KDM1AHDAC8HDAC6KCNQ4KCNQ5
	SCHEMBL3065683	0.73	BCL2A1 (0.42)	KDM1AHDAC8HDAC6KCNQ4KCNQ5
	SCHEMBL16640701	0.73	NR1H4 (0.38)	BCL2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.