Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3057 | 1.00 | CTSB (0.43) | CTSBSCN9AMYCWDR5ADAM17 | |
| SCHEMBL16839778 | 0.84 | ATM (0.49) | CTSBSCN9AHRH3LTA4HTAS1R3 | |
| SCHEMBL16839746 | 0.84 | ATM (0.49) | CTSBSCN9AHRH3LTA4HTAS1R3 | |
| SCHEMBL3536 | 0.82 | MEN1 (0.44) | MYCWDR5ADAM17OXTRAVPR1A | |
| SCHEMBL3537 | 0.82 | MEN1 (0.44) | MYCWDR5ADAM17OXTRAVPR1A | |
| SCHEMBL2260 | 0.82 | ATM (0.42) | MYCWDR5ADAM17OXTRAVPR1A | |
| SCHEMBL4489378 | 0.80 | CTSB (0.47) | CTSBLTA4HTAS1R3TAS1R1 | |
| SCHEMBL7890595 | 0.80 | CTSB (0.47) | CTSBLTA4HTAS1R3TAS1R1 | |
| SCHEMBL13282255 | 0.80 | CTSB (0.47) | CTSBLTA4HTAS1R3TAS1R1 | |
| SCHEMBL4488175 | 0.78 | SSTR3 (0.56) | CTSBSCN9AHRH3TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |