Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAP2 | P11137 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28080968 | 0.79 | ALDH1A1 (0.41) | PARP1ALDH1A1HTTHPGDKDM4E | |
| SCHEMBL26112712 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HTTHPGDKDM4EALOX15 | |
| SCHEMBL3494606 | 0.71 | MAPT (0.43) | ALDH1A1HTTHPGDKDM4EHSD17B10 | |
| SCHEMBL4792528 | 0.69 | PARP1 (0.45) | PARP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL29750764 | 0.68 | CCNC (0.51) | PARP1ALDH1A1HTTHPGDALOX15 | |
| SCHEMBL12912923 | 0.67 | PARP1 (0.44) | PARP1ALDH1A1HTTHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL28338871 | 0.67 | CHEK1 (0.44) | PARP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL29264066 | 0.67 | LMNA (0.44) | PARP1ALDH1A1HTTHPGDKDM4E | |
| SCHEMBL9459084 | 0.67 | HTT (0.50) | PARP1ALDH1A1HTTALOX15KMT2A | |
| SCHEMBL5534778 | 0.67 | ALDH1A1 (0.47) | PARP1ALDH1A1HTTHPGDHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504341-A1 | COMPOUNDS THAT INTERACT WITH RAS SUPERFAMILY PROTEINS FOR TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | Shy Therapeutics LLC (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023196975-A1 | COMPOUNDS THAT INTERACT WITH RAS SUPERFAMILY PROTEINS FOR TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | SHY THERAPEUTICS, LLC (US) | 2023-10-12 | — | — | WO | disclosed |