Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29543448 | 0.79 | KMT2A (0.48) | RAB9A | |
| SCHEMBL31275168 | 0.78 | KIF11 (0.47) | CES2CES1GRM4 | |
| SCHEMBL25369533 | 0.77 | CES2 (0.55) | SRD5A2CES2CNR2 | |
| SCHEMBL27780305 | 0.77 | NOTUM (0.35) | SRD5A2CES2CNR2VNN1NPC1 | |
| SCHEMBL135361 | 0.77 | KMT2A (0.50) | SRD5A2CES2CES1CNR2NPC1 | |
| SCHEMBL6002659 | 0.76 | NPC1 (0.54) | EPHX2NPC1RAB9A | |
| SCHEMBL27717744 | 0.75 | SRD5A2 (0.50) | SRD5A2CES2CES1GSK3BPTPN1 | |
| SCHEMBL1273234 | 0.75 | — | — | |
| SCHEMBL648641 | 0.75 | SRD5A2 (0.83) | SRD5A2CES2CES1GSK3BPTPN1 | |
| Hydrochloric Acid SCHEMBL27733522 | 0.73 | SRD5A2 (0.79) | SRD5A2CES2CES1GSK3BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4496570-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | The Scripps Research Institute (US) | 2025-01-29 | — | — | EP | disclosed |
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |