Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21403919 | 1.00 | GABRA1 (0.79) | GABRA1GABRA5 | |
| SCHEMBL29421368 | 0.93 | GABRA5 (0.79) | GABRA1GABRA5 | |
| SCHEMBL20241274 | 0.93 | GABRA5 (0.79) | GABRA1GABRA5 | |
| SCHEMBL30592886 | 0.93 | GABRA5 (0.79) | GABRA1GABRA5 | |
| SCHEMBL20241113 | 0.89 | GABRA1 (0.82) | GABRA1GABRA5 | |
| SCHEMBL30592788 | 0.89 | GABRA1 (0.82) | GABRA1GABRA5 | |
| SCHEMBL2924603 | 0.89 | GABRA5 (0.84) | GABRA1GABRA5 | |
| SCHEMBL20241313 | 0.89 | GABRA1 (0.70) | GABRA1GABRA5 | |
| SCHEMBL30592825 | 0.89 | GABRA1 (0.70) | GABRA1GABRA5 | |
| SCHEMBL20241395 | 0.88 | GABRA1 (1.00) | GABRA1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285525-A | Novel isoxazolyl ether derivatives as GABAA alpha 5PAM | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-109923113-B | Isoxazolyl ether derivatives as GABA A alpha 5 PAM | 豪夫迈·罗氏有限公司 | 2023-10-13 | — | — | CN | disclosed |