Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26608399 | 1.00 | POLB (0.49) | POLBRAB9AKMT2AALDH1A1NPC1 | |
| SCHEMBL31336221 | 0.94 | KMT2A (0.47) | RAB9AKMT2AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL26601732 | 0.94 | KMT2A (0.47) | RAB9AKMT2AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL26608371 | 0.88 | ALDH1A1 (0.48) | POLBKMT2AALDH1A1PTPN1LMNA | |
| SCHEMBL31336280 | 0.87 | ALDH1A1 (0.43) | POLBRAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL26608206 | 0.87 | ALDH1A1 (0.43) | POLBRAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL31336263 | 0.85 | KMT2A (0.48) | POLBRAB9AKMT2AALDH1A1NPC1 | |
| SCHEMBL31336276 | 0.85 | RAB9A (0.51) | RAB9AKMT2AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL26608464 | 0.85 | KMT2A (0.48) | POLBRAB9AKMT2AALDH1A1NPC1 | |
| SCHEMBL26608329 | 0.85 | RAB9A (0.51) | RAB9AKMT2AALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119546580-A | Heteroaryl compounds for the treatment of pain | 沃泰克斯药物股份有限公司 | 2025-02-28 | — | — | CN | disclosed |
| EP-4511115-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | Vertex Pharmaceuticals Incorporated (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023205468-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-10-26 | — | — | WO | disclosed |