Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.61 |
| ▸ | KDM4C | Q9H3R0 | 18/20 | 0.59 |
| ▸ | KDM5A | P29375 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM4B | O94953 | 1/20 | 0.50 |
| ▸ | KDM5C | P41229 | 1/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.50 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25190918 | 1.00 | QTRT1 (0.61) | QTRT1KDM4CKDM5AMAPTKDM4A | |
| SCHEMBL16908336 | 0.79 | KDM4C (0.59) | KDM4CKDM5AMAPTKDM4AKDM4B | |
| SCHEMBL29656611 | 0.79 | KDM4C (0.68) | KDM4CKDM5AMAPTKDM4AKDM4B | |
| SCHEMBL8279823 | 0.79 | KDM4C (0.68) | KDM4CKDM5AMAPTKDM4AKDM4B | |
| SCHEMBL15644528 | 0.79 | KDM4C (0.59) | KDM4CKDM5AMAPTKDM4AKDM4B | |
| SCHEMBL26017641 | 0.79 | KDM4C (0.59) | KDM4CKDM5AMAPTKDM4AKDM4B | |
| Hydrochloric Acid SCHEMBL15645443 | 0.77 | KDM4C (0.58) | KDM4CKDM5AMAPTKDM4AKDM4B | |
| Hydrochloric Acid SCHEMBL15645503 | 0.77 | KDM4C (0.58) | KDM4CKDM5AMAPTKDM4AKDM4B | |
| SCHEMBL15645718 | 0.76 | KDM4C (0.82) | KDM4CKDM5AMAPT | |
| SCHEMBL103994 | 0.76 | QTRT1 (1.00) | QTRT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472047-B | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-116472047-A | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-07-21 | — | — | CN | disclosed |