Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25406752 | 0.85 | OPRK1 (0.50) | HRH4HRH3 | |
| SCHEMBL30338745 | 0.85 | OPRK1 (0.50) | HRH4HRH3 | |
| SCHEMBL2366907 | 0.83 | HRH4 (0.48) | HRH4HTTMEN1CYP1A2CYP3A4 | |
| SCHEMBL19446958 | 0.82 | HRH4 (0.48) | HRH4MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1745337 | 0.82 | KDM4E (0.36) | HRH4HRH3ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL20605140 | 0.81 | HRH4 (0.53) | HRH4HRH3HTTSMN1; SMN2 | |
| SCHEMBL29969981 | 0.81 | HRH4 (0.53) | HRH4HRH3HTTSMN1; SMN2 | |
| SCHEMBL24970193 | 0.81 | HRH4 (0.47) | HRH4HRH3HTTALDH1A1CYP1A2 | |
| SCHEMBL1707795 | 0.81 | ALDH1A1 (0.44) | MEN1ALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL27829786 | 0.81 | OPRK1 (0.37) | HRH4HRH3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472047-B | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-116472047-A | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-07-21 | — | — | CN | disclosed |