Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070768 | 0.81 | WDR5 (0.59) | WDR5LDHAMAPTSLC22A12ALDH1A1 | |
| SCHEMBL28224492 | 0.79 | WDR5 (0.49) | WDR5LDHAMAPTSLC22A12CYP1B1 | |
| SCHEMBL2240626 | 0.77 | WDR5 (0.81) | WDR5LDHAMAPTALDH1A1TSHR | |
| SCHEMBL9856947 | 0.77 | WDR5 (0.63) | WDR5LDHAMAPTALDH1A1CYP2A6 | |
| SCHEMBL30595041 | 0.76 | WDR5 (0.43) | WDR5LDHAMAPTSLC22A12ALDH1A1 | |
| SCHEMBL29125515 | 0.76 | WDR5 (0.43) | WDR5LDHAMAPTSLC22A12ALDH1A1 | |
| SCHEMBL29125513 | 0.76 | WDR5 (0.43) | WDR5LDHAMAPTSLC22A12ALDH1A1 | |
| SCHEMBL6956573 | 0.75 | WDR5 (0.52) | WDR5LDHAMAPTALDH1A1CYP2A6 | |
| SCHEMBL30595028 | 0.74 | WDR5 (0.41) | WDR5LDHAMAPTALDH1A1CYP1B1 | |
| SCHEMBL27927917 | 0.74 | WDR5 (0.59) | WDR5LDHAMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024477-A | Preparation method of aliphatic chain substituted biphenyl type or phenyl pyrrole type chiral monophosphine ligand | 南京大学 | 2023-11-10 | — | — | CN | disclosed |