Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18821319 | 0.84 | HPRT1 (0.41) | WDR5PRSS1F2PLAUKLKB1 | |
| SCHEMBL27927917 | 0.84 | WDR5 (0.59) | WDR5LDHATDP1KDM4EMAPT | |
| SCHEMBL18821313 | 0.83 | HPRT1 (0.43) | WDR5LDHAPRSS1TDP1F2 | |
| SCHEMBL9856947 | 0.79 | WDR5 (0.63) | WDR5LDHATDP1KDM4EMAPT | |
| SCHEMBL2240626 | 0.79 | WDR5 (0.81) | WDR5LDHATDP1KDM4EMAPT | |
| SCHEMBL17070768 | 0.76 | WDR5 (0.59) | WDR5LDHATDP1MAPTKMT2A | |
| SCHEMBL18821318 | 0.76 | MEN1 (0.35) | WDR5PRSS1F2KDM4EMAPT | |
| SCHEMBL11486740 | 0.76 | WDR5 (0.44) | WDR5PRSS1F2PLAUKLKB1 | |
| SCHEMBL30595049 | 0.75 | WDR5 (0.49) | WDR5LDHATDP1MAPTALDH1A1 | |
| SCHEMBL29435310 | 0.75 | ALDH1A1 (0.44) | WDR5LDHAPRSS1TDP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798295-B1 | NOVEL AMIDINONAPHTHYL DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 2003-02-26 | — | — | EP | disclosed |
| US-6333320-B1 | USEFUL AS DRUGS, ESPECIALLY AS AN ACTIVATED BLOOD COAGULATION FACTOR X INHIBITOR | Yamanouchi Pharmaceutical Co. (JP) | 2001-12-25 | — | — | US | disclosed |
| EP-1000936-A1 | NOVEL HEXAHYDRO-1,4-DIAZEPINE DERIVATIVES OR SALTS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5869501-A | PREVENTION AND/OR TREATMENT OF DISEASES CAUSED BY THROMBUS OR EMBOLUS. | YAMANOUCHI PHARMACEUTICAL CO. LTD (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0798295-A1 | NOVEL AMIDINONAPHTHYL DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |