Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 8/20 | 0.58 |
| ▸ | BCHE | P06276 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11409331 | 1.00 | CES1 (0.58) | CES1BCHEALDH1A1CES2GAA | |
| SCHEMBL30596238 | 1.00 | CES1 (0.58) | CES1BCHEALDH1A1CES2GAA | |
| SCHEMBL11561791 | 0.89 | CES1 (0.50) | CES1BCHEALDH1A1CES2GAA | |
| SCHEMBL11561782 | 0.81 | CES1 (0.53) | CES1BCHEALDH1A1CES2GAA | |
| SCHEMBL9735350 | 0.81 | CES1 (0.49) | CES1BCHEALDH1A1CES2GAA | |
| SCHEMBL2978831 | 0.80 | MAPK14 (0.46) | CES1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7166267 | 0.80 | CES1 (0.47) | CES1BCHEALDH1A1CES2GAA | |
| SCHEMBL2890089 | 0.76 | KMT2A (0.60) | MEN1KMT2AMAPK14CYP3A4MGLL | |
| Phenyl Isatin SCHEMBL916808 | 0.73 | CES1 (1.00) | CES1BCHEALDH1A1CES2GAA | |
| SCHEMBL3061805 | 0.73 | APP (0.51) | ALDH1A1GAANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836102-A | Method for preparing sodium diclofenac chloro impurity (3-chloro-N- (2, 6-dichlorophenyl) indol-2-one) | 河南东泰制药有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-116836102-A | Method for preparing sodium diclofenac chloro impurity (3-chloro-N- (2, 6-dichlorophenyl) indol-2-one) | 河南东泰制药有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116836102-A | Method for preparing sodium diclofenac chloro impurity (3-chloro-N- (2, 6-dichlorophenyl) indol-2-one) | 河南东泰制药有限公司 | 2023-10-03 | — | — | CN | disclosed |