Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 7/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 10/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30596250 | 0.75 | PDE4D (1.00) | PDE4DPDE4BLRRK2 | |
| SCHEMBL30596260 | 0.70 | PDE4D (0.86) | PDE4DPDE4BIRAK4 | |
| SCHEMBL16985496 | 0.69 | LRRK2 (0.53) | LRRK2 | |
| SCHEMBL30596271 | 0.68 | PDE4D (0.78) | PDE4DPDE4BIRAK4 | |
| SCHEMBL31638144 | 0.68 | FLT3 (0.38) | PDE4DPDE4BFLT3SYK | |
| SCHEMBL30596273 | 0.68 | PDE4D (0.85) | PDE4DPDE4BLRRK2 | |
| SCHEMBL31586421 | 0.67 | IRAK4 (0.40) | LRRK2IRAK4 | |
| SCHEMBL30596251 | 0.67 | PDE4D (0.61) | PDE4DPDE4B | |
| SCHEMBL30596264 | 0.67 | PDE4D (0.61) | PDE4DPDE4B | |
| SCHEMBL30596270 | 0.65 | PDE4D (0.50) | PDE4DPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836162-A | Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof | 南方医科大学 | 2023-10-03 | — | — | CN | disclosed |