Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 8/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.61 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30596251 | 0.88 | PDE4D (0.61) | PDE4DPDE4BS1PR2MAPTL3MBTL1 | |
| SCHEMBL30596271 | 0.78 | PDE4D (0.78) | PDE4DPDE4BS1PR2L3MBTL1POLB | |
| SCHEMBL30596272 | 0.76 | PDE4D (0.59) | PDE4DPDE4BMEN1KMT2AKDM4E | |
| SCHEMBL30596260 | 0.73 | PDE4D (0.86) | PDE4DPDE4BS1PR2L3MBTL1MEN1 | |
| SCHEMBL30596261 | 0.69 | PDE4D (0.59) | PDE4DPDE4BMEN1KMT2APOLB | |
| SCHEMBL30596246 | 0.67 | PDE4D (0.60) | PDE4DPDE4B | |
| SCHEMBL30596270 | 0.65 | PDE4D (0.50) | PDE4DPDE4BMAPTMEN1KMT2A | |
| SCHEMBL30596249 | 0.63 | PDE4D (0.77) | PDE4DPDE4BS1PR2MEN1HPGD | |
| SCHEMBL15525073 | 0.63 | ALDH1A1 (0.51) | PDE4DPDE4BL3MBTL1MEN1HPGD | |
| SCHEMBL11631341 | 0.62 | ALDH1A1 (0.43) | HPGDKMT2APOLBTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836162-A | Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof | 南方医科大学 | 2023-10-03 | — | — | CN | disclosed |