Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 8/20 | 0.78 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.78 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30596260 | 0.85 | PDE4D (0.86) | PDE4DPDE4BS1PR2L3MBTL1IRAK4 | |
| SCHEMBL30596251 | 0.78 | PDE4D (0.61) | PDE4DPDE4BS1PR2POLBL3MBTL1 | |
| SCHEMBL30596264 | 0.78 | PDE4D (0.61) | PDE4DPDE4BS1PR2POLBL3MBTL1 | |
| SCHEMBL30596249 | 0.72 | PDE4D (0.77) | PDE4DPDE4BS1PR2POLBKDM4E | |
| SCHEMBL30596246 | 0.68 | PDE4D (0.60) | PDE4DPDE4BIRAK4 | |
| SCHEMBL30596270 | 0.67 | PDE4D (0.50) | PDE4DPDE4BALDH1A1 | |
| SCHEMBL30596272 | 0.66 | PDE4D (0.59) | PDE4DPDE4BGAAKDM4EALDH1A1 | |
| SCHEMBL30596261 | 0.66 | PDE4D (0.59) | PDE4DPDE4BPOLBGAAKDM4E | |
| SCHEMBL11494319 | 0.65 | HTT (0.45) | POLBL3MBTL1HTTGAAKDM4E | |
| SCHEMBL15525073 | 0.64 | ALDH1A1 (0.51) | PDE4DPDE4BPOLBL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836162-A | Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof | 南方医科大学 | 2023-10-03 | — | — | CN | disclosed |