Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087314 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP19A1ALDH1A1HTTLARS1 | |
| SCHEMBL28003775 | 0.83 | SMN1; SMN2 (0.74) | SMN1; SMN2CYP19A1ALDH1A1HTTLARS1 | |
| SCHEMBL28195553 | 0.81 | HTT (0.75) | SMN1; SMN2CYP19A1ALDH1A1HTTLMNA | |
| SCHEMBL5597899 | 0.80 | ALDH1A1 (0.72) | SMN1; SMN2CYP19A1ALDH1A1HTTLMNA | |
| SCHEMBL28004245 | 0.80 | ALDH1A1 (0.72) | SMN1; SMN2CYP19A1ALDH1A1HTTLMNA | |
| SCHEMBL5597888 | 0.79 | GAA (0.71) | ALDH1A1HTTLMNA | |
| SCHEMBL13972833 | 0.78 | NAMPT (0.55) | SMN1; SMN2CYP19A1ALDH1A1HTTLMNA | |
| SCHEMBL13959238 | 0.78 | NAMPT (0.55) | SMN1; SMN2CYP19A1ALDH1A1HTTLMNA | |
| SCHEMBL3913276 | 0.78 | NAMPT (0.57) | SMN1; SMN2CYP19A1ALDH1A1HTTLMNA | |
| SCHEMBL28113867 | 0.78 | CA1 (0.64) | SMN1; SMN2ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116806217-A | Substituted cyclic modulators of protein phosphatase 2A (PP 2A) and methods of use thereof | 拉帕塔疗法公司 | 2023-09-26 | — | — | CN | disclosed |