Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.53 |
| ▸ | GRB2 | P62993 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31566096 | 0.92 | TLR2 (0.55) | TLR2PTPN1 | |
| SCHEMBL20758974 | 0.92 | TLR2 (0.55) | TLR2PTPN1 | |
| SCHEMBL20758846 | 0.92 | TLR2 (0.55) | TLR2PTPN1 | |
| SCHEMBL20759079 | 0.92 | TLR2 (0.55) | TLR2PTPN1 | |
| SCHEMBL30193301 | 0.91 | TLR2 (0.53) | TLR2PTPN1CTSL | |
| SCHEMBL30150290 | 0.91 | TLR2 (0.53) | TLR2PTPN1CTSL | |
| SCHEMBL30598967 | 0.91 | TLR2 (0.55) | TLR2PTPN1 | |
| SCHEMBL14374768 | 0.90 | PTPN1 (0.55) | TLR2PTPN1GRB2CTSL | |
| SCHEMBL31138058 | 0.89 | PTPN1 (0.57) | TLR2PTPN1GRB2 | |
| SCHEMBL8371529 | 0.88 | TLR2 (0.51) | TLR2PTPN1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017172881-A1 | THERMOGENIC COMPOSITIONS AND METHODS | OHIO STATE INNOVATION FOUNDATION (US) | 2017-10-05 | — | — | WO | disclosed |