Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | EPOR | P19235 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24838734 | 0.89 | LMNA (0.48) | SMPD1SMN1; SMN2GABRA5NPC1RAB9A | |
| SCHEMBL25194754 | 0.89 | SMPD1 (0.41) | SMPD1SMN1; SMN2GABRA5NPC1RAB9A | |
| SCHEMBL24788994 | 0.89 | SMPD1 (0.48) | SMPD1SMN1; SMN2GABRA5NPC1RAB9A | |
| SCHEMBL21458792 | 0.87 | SMPD1 (0.40) | SMPD1SMN1; SMN2GABRA5NPC1RAB9A | |
| SCHEMBL25214008 | 0.82 | ADRB2 (0.36) | SMPD1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL26683459 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL27151955 | 0.82 | SMPD1 (0.39) | SMPD1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL31681495 | 0.80 | KMT2A (0.35) | SMPD1SMN1; SMN2GABRA5NPC1RAB9A | |
| SCHEMBL21405138 | 0.80 | SMPD1 (0.40) | SMPD1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL25276739 | 0.79 | ACACB (0.38) | SMPD1SMN1; SMN2NPC1RAB9AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023185864-A1 | Compounds for Targeted Degradation of KRAS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2023-10-05 | — | — | WO | disclosed |