SCHEMBL30599100

SCHEMBL30599100

COCC12CC(C)CC(C1)N2C(=O)c1ccccn1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SNRNP200 O75643 10/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA7 P36544 1/20 0.39
CHRNA4 P43681 1/20 0.39
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
DRD2 P14416 1/20 0.37
CCR8 P51685 1/20 0.37
KCNH2 Q12809 1/20 0.37
RBP4 P02753 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
EPHX1 P07099 1/20 0.36
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30886401 0.91 SNRNP200 (0.38) SNRNP200L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL30599098 0.88 SNRNP200 (0.41) SNRNP200L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL30599101 0.88 SNRNP200 (0.41) SNRNP200L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL30599154 0.87 L3MBTL1 (0.43) SNRNP200L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL31284947 0.87 SNRNP200 (0.41) SNRNP200L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL31284744 0.85 SNRNP200 (0.42) SNRNP200L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL30886553 0.82 L3MBTL1 (0.40) SNRNP200L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL26923441 0.80 L3MBTL1 (0.42) SNRNP200L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL26951676 0.80 L3MBTL1 (0.42) SNRNP200L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL26951677 0.80 L3MBTL1 (0.42) SNRNP200L3MBTL1CHRNB2CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598927-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Tenvie Therapeutics Inc. (US) 2025-08-13 EP disclosed
EP-4486722-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Nico Therapeutics, Inc. (US) 2025-01-08 EP disclosed
CN-119137101-A Compounds, compositions, and methods 尼科治疗有限公司 2024-12-13 CN disclosed
WO-2024077273-A2 COMPOUNDS, COMPOSITIONS, AND METHODS DENALI THERAPEUTICS INC. (US) 2024-04-11 WO disclosed
WO-2023168298-A2 COMPOUNDS, COMPOSITIONS, AND METHODS DENALI THERAPEUTICS INC. (US) 2023-09-07 WO disclosed