SCHEMBL30599101

SCHEMBL30599101

CC1CC2CC(COC(F)F)(C1)N2C(=O)c1ccccn1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SNRNP200 O75643 10/20 0.41
L3MBTL1 Q9Y468 1/20 0.38
RBP4 P02753 3/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA7 P36544 1/20 0.37
CHRNA4 P43681 1/20 0.37
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
EPHX1 P07099 1/20 0.35
EPHX2 P34913 1/20 0.35
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30599098 1.00 SNRNP200 (0.41) SNRNP200L3MBTL1RBP4CHRNB2CHRNB4
SCHEMBL30599100 0.88 SNRNP200 (0.41) SNRNP200L3MBTL1RBP4CHRNB2CHRNB4
SCHEMBL30599154 0.85 L3MBTL1 (0.43) SNRNP200L3MBTL1RBP4CHRNB2CHRNB4
SCHEMBL30886401 0.84 SNRNP200 (0.38) SNRNP200L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL31284744 0.83 SNRNP200 (0.42) SNRNP200L3MBTL1RBP4CHRNB2CHRNB4
SCHEMBL31284947 0.82 SNRNP200 (0.41) SNRNP200L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL26257762 0.76 SNRNP200 (0.42) SNRNP200L3MBTL1RBP4CHRNB2CHRNB4
SCHEMBL25436435 0.75 L3MBTL1 (0.44) SNRNP200L3MBTL1RBP4CHRNB2CHRNB4
SCHEMBL25432813 0.75 L3MBTL1 (0.44) SNRNP200L3MBTL1RBP4CHRNB2CHRNB4
SCHEMBL26923787 0.75 L3MBTL1 (0.44) SNRNP200L3MBTL1RBP4CHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4486722-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Nico Therapeutics, Inc. (US) 2025-01-08 EP disclosed
WO-2023168298-A2 COMPOUNDS, COMPOSITIONS, AND METHODS DENALI THERAPEUTICS INC. (US) 2023-09-07 WO disclosed