Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.55 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418501 | 1.00 | CYP11B2 (0.55) | CYP11B2EIF2AK4GPR119NAMPTCYP3A4 | |
| SCHEMBL25223238 | 1.00 | CYP11B2 (0.55) | CYP11B2EIF2AK4GPR119NAMPTCYP3A4 | |
| SCHEMBL30599709 | 0.95 | CYP11B2 (0.59) | CYP11B2EIF2AK4GPR119NAMPTCYP3A4 | |
| SCHEMBL25222484 | 0.95 | CYP11B2 (0.59) | CYP11B2EIF2AK4GPR119NAMPTCYP3A4 | |
| SCHEMBL25224809 | 0.91 | GPR119 (0.51) | CYP11B2EIF2AK4GPR119NAMPTCYP3A4 | |
| SCHEMBL29418351 | 0.91 | GPR119 (0.51) | CYP11B2EIF2AK4GPR119NAMPTCYP3A4 | |
| SCHEMBL25209734 | 0.84 | GPR119 (0.54) | GPR119CYP3A4POLB | |
| SCHEMBL30599749 | 0.84 | GPR119 (0.54) | GPR119CYP3A4POLB | |
| SCHEMBL25219083 | 0.83 | CYP3A4 (0.43) | CYP11B2CYP3A4CYP2D6CYP2C9CYP11B1 | |
| SCHEMBL38662223 | 0.82 | CYP3A4 (0.62) | CYP11B2CYP3A4CYP2D6CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917279-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-10-20 | — | — | CN | disclosed |