Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24127248 | 0.89 | SPR (0.52) | USP30GPR119SPRKDM4ERET | |
| SCHEMBL21424901 | 0.88 | PROKR1 (0.49) | USP30GPR119SPRHPGDTP53 | |
| SCHEMBL32661690 | 0.86 | GPR119 (0.56) | USP30GPR119KDM4ERETHPGD | |
| SCHEMBL38661435 | 0.80 | GPR119 (0.46) | USP30GPR119RET | |
| SCHEMBL21429735 | 0.79 | HTRA1 (0.43) | USP30GPR119HCAR2SPRRET | |
| SCHEMBL21429667 | 0.79 | HTRA1 (0.43) | USP30GPR119HCAR2SPRRET | |
| SCHEMBL25297123 | 0.78 | POLB (0.43) | GPR119KDM4ENR1H2HPGDRORC | |
| SCHEMBL23981632 | 0.78 | GPR119 (0.44) | USP30GPR119KDM4ERET | |
| SCHEMBL24002057 | 0.78 | USP30 (0.46) | USP30GPR119NR1H2RET | |
| SCHEMBL19979269 | 0.78 | USP30 (0.50) | USP30GPR119NR1H2RETHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499656-A1 | STAT MODULATORS AND USES THEREOF | Recludix Pharma, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| CN-119183453-A | STAT modulators and uses thereof | 瑞克鲁迪克斯制药股份有限公司 | 2024-12-24 | — | — | CN | disclosed |
| WO-2023192960-A1 | STAT MODULATORS AND USES THEREOF | RECLUDIX PHARMA, INC. (US) | 2023-10-05 | — | — | WO | disclosed |