SCHEMBL30600352

SCHEMBL30600352

Oc1ccccc1-c1cccc2c1[nH]c1ccccc12

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 16/20 0.59
IMPDH2 P12268 1/20 0.52
IMPDH1 P20839 1/20 0.52
KIF11 P52732 1/20 0.52
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CDK4 P11802 1/20 0.49
CCND1 P24385 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15455181 1.00 PARP14 (0.59) PARP14IMPDH2IMPDH1KIF11CA1
SCHEMBL4280269 0.89 PARP14 (0.56) PARP14IMPDH2IMPDH1KIF11CA1
SCHEMBL29733506 0.88 KIF11 (0.63) PARP14KIF11
SCHEMBL208113 0.88 KIF11 (0.63) PARP14KIF11
SCHEMBL3626311 0.88 PARP14 (0.55) PARP14IMPDH2IMPDH1KIF11CA1
Carbazole SCHEMBL27571745 0.86 ALDH1A1 (0.64) IMPDH2IMPDH1KIF11CA1CA2
SCHEMBL191654 0.86 KIF11 (0.61) PARP14KIF11
SCHEMBL30521516 0.86 KIF11 (0.61) PARP14KIF11
SCHEMBL51674 0.86 KIF11 (0.61) PARP14KIF11
SCHEMBL329557 0.84 AR (0.62) PARP14IMPDH2IMPDH1KIF11CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116891585-A Preparation method of soluble polyaryletherketone film with low toxicity solvent 大连中科聚合新材料科技有限公司 2023-10-17 CN disclosed