Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3204064 | 1.00 | POLB (0.48) | POLBKMT2ACYP2A6MAOAMAOB | |
| SCHEMBL3992123 | 0.91 | POLB (0.52) | POLBKMT2AALDH1A1HTTELANE | |
| SCHEMBL454827 | 0.81 | POLB (0.67) | POLBKMT2AMAOAMAOBHTT | |
| SCHEMBL25210408 | 0.79 | ALDH1A1 (0.39) | POLBKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL28160078 | 0.78 | POLB (0.64) | POLBKMT2AMAOAMAOBHTT | |
| SCHEMBL2022462 | 0.78 | POLB (0.64) | POLBKMT2AMAOAMAOBHTT | |
| SCHEMBL30718167 | 0.77 | DDB1 (0.44) | POLBKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL29569183 | 0.74 | KMT2A (0.67) | KMT2ACYP2A6MAOAMAOBALDH1A1 | |
| SCHEMBL23832541 | 0.74 | KMT2A (0.67) | KMT2ACYP2A6MAOAMAOBALDH1A1 | |
| SCHEMBL11606022 | 0.72 | POLB (0.47) | POLBKMT2AALDH1A1ELANEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546256-A | Method for exogenous drug activation of chemical-induced signaling complexes expressed in engineered cells in vitro and in vivo | 西雅图儿童医院（DBA西雅图儿童研究所） | 2024-08-27 | — | — | CN | disclosed |
| CN-110191955-B | Method for exogenous drug activation of chemical-induced signaling complexes expressed in engineered cells in vitro and in vivo | 西雅图儿童医院（DBA西雅图儿童研究所） | 2024-05-31 | — | — | CN | disclosed |
| CN-110621664-B | Novel piperidine-2, 6-dione derivatives and uses thereof | 韩国化学研究院 | 2023-08-01 | — | — | CN | disclosed |