Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654154 | 1.00 | KMT2A (0.45) | KMT2AHPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL135312 | 0.91 | KMT2A (0.47) | KMT2AHPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL31305194 | 0.91 | KMT2A (0.47) | KMT2AHPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3655864 | 0.89 | HPGD (0.45) | HPGDCYP1A2CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL17739304 | 0.88 | CA1 (0.41) | KMT2AHPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6680706 | 0.84 | ALDH1A1 (0.53) | KMT2ACYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL1205921 | 0.83 | TSHR (0.47) | HPGDL3MBTL1TSHRNAMPTALDH1A1 | |
| SCHEMBL3101339 | 0.83 | TSHR (0.51) | KMT2AHPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7403833 | 0.83 | ADRB2 (0.44) | KMT2ACYP3A4L3MBTL1TSHRNAMPT | |
| SCHEMBL474165 | 0.82 | DTYMK (0.44) | KMT2AHPGDCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621664-B | Novel piperidine-2, 6-dione derivatives and uses thereof | 韩国化学研究院 | 2023-08-01 | — | — | CN | disclosed |