Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | F12 | P00748 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26675308 | 1.00 | ALOX15 (0.47) | ALOX15HSD17B10F2MAPTHTT | |
| SCHEMBL26675432 | 0.96 | ALOX15 (0.48) | ALOX15HSD17B10F2MAPTHTT | |
| Trifluoroacetic Acid SCHEMBL26675303 | 0.89 | ALOX15 (0.45) | ALOX15HSD17B10F2MAPTHTT | |
| SCHEMBL26834621 | 0.86 | ALOX15 (0.49) | ALOX15HSD17B10F2MAPTHTT | |
| SCHEMBL29767945 | 0.86 | ALOX15 (0.49) | ALOX15HSD17B10F2MAPTHTT | |
| SCHEMBL30600511 | 0.86 | ENPP3 (0.41) | MAPTHTTSMN1; SMN2TP53PKM | |
| SCHEMBL26675349 | 0.86 | ENPP3 (0.41) | MAPTHTTSMN1; SMN2TP53PKM | |
| SCHEMBL29767952 | 0.86 | ALOX15 (0.47) | ALOX15HSD17B10F2MAPTHTT | |
| SCHEMBL26675344 | 0.86 | ALOX15 (0.47) | ALOX15HSD17B10F2MAPTHTT | |
| SCHEMBL26834610 | 0.86 | ALOX15 (0.47) | ALOX15HSD17B10F2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867782-A | Pyrazole amide derivative | 豪夫迈·罗氏有限公司 | 2023-10-10 | — | — | CN | claimed |
| CN-116867782-A | Pyrazole amide derivative | 豪夫迈·罗氏有限公司 | 2023-10-10 | — | — | CN | disclosed |