Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28701831 | 1.00 | OPRK1 (0.44) | OPRK1LMNAPDE3APDE4DCHRM2 | |
| SCHEMBL28700922 | 0.83 | KMT2A (0.45) | LMNAALDH1A1KMT2AMEN1AADAT | |
| SCHEMBL28685073 | 0.77 | MEN1 (0.55) | LMNAALDH1A1KMT2AMEN1AADAT | |
| SCHEMBL23892731 | 0.76 | AADAT (0.42) | OPRK1LMNAPDE3APDE4DCHRM2 | |
| SCHEMBL28226709 | 0.74 | CHEK1 (0.53) | OPRK1LMNAPDE3APDE4DCHRM2 | |
| SCHEMBL10743139 | 0.72 | MEN1 (0.40) | OPRK1LMNAPDE3APDE4DCHRM2 | |
| SCHEMBL8785808 | 0.71 | OPRK1 (0.44) | OPRK1LMNAPDE3APDE4DCHRM2 | |
| SCHEMBL11466184 | 0.70 | OPRK1 (0.43) | OPRK1LMNAPDE3APDE4DCHRM2 | |
| SCHEMBL9156773 | 0.70 | EGFR (0.41) | LMNACA12CA2CA4CA7 | |
| SCHEMBL18189471 | 0.69 | KMT2A (0.52) | OPRK1LMNAPDE3APDE4DCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999158-B | 3- (1-hydroxyalkylene) indolone and preparation method thereof | 延边大学 | 2023-08-01 | — | — | CN | disclosed |