Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421695 | 0.93 | DNM1 (0.35) | CHRM2DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL3460398 | 0.84 | PLA2G1B (0.39) | ALDH1A1PLA2G1BPLA2G2AOPRM1 | |
| SCHEMBL1448309 | 0.83 | DNM1 (0.39) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL5078140 | 0.82 | CHRM2 (0.42) | CHRM2DNM1TSHRNFKB1GSR | |
| SCHEMBL5167308 | 0.80 | PLA2G1B (0.36) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL1605060 | 0.80 | PLA2G1B (0.47) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3237512 | 0.79 | FDPS (0.36) | PLA2G1BPLA2G2AOPRM1 | |
| SCHEMBL15477624 | 0.76 | PLA2G1B (0.50) | DNM1PLA2G1BPLA2G2AOPRM1 | |
| SCHEMBL6908178 | 0.76 | PLA2G1B (0.50) | DNM1PLA2G1BPLA2G2AOPRM1 | |
| SCHEMBL29767944 | 0.75 | DNM1 (0.46) | CHRM2DNM1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100047360-A1 | Use Of Polyamines In The Treatment Of Psoriasis | Bioforskining Pharma AS (NO) | 2010-02-25 | — | — | US | disclosed |
| EP-2004162-A1 | USE OF POLYAMINES IN THE TREATMENT OF PSORIASIS | Bioforskning Pharma AS (NO) | 2008-12-24 | — | — | EP | disclosed |
| US-20080124312-A1 | Polyamine Compositions | BIOFORSKNING AS (NO) | 2008-05-29 | — | — | US | disclosed |
| WO-2007104981-A1 | USE OF POLYAMINES IN THE TREATMENT OF PSORIASIS | BIOFORSKNING PHARMA AS (NO) | 2007-09-20 | — | — | WO | disclosed |