Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401235 | 1.00 | CASP3 (0.46) | CASP3PIN1KMT2APOLBCYP3A4 | |
| SCHEMBL29692865 | 0.91 | CASP3 (0.47) | CASP3PIN1KMT2APOLBEPHX2 | |
| SCHEMBL3070048 | 0.90 | CASP3 (0.52) | CASP3PIN1KMT2AEPHX2 | |
| SCHEMBL29401786 | 0.90 | CASP3 (0.52) | CASP3PIN1KMT2AEPHX2 | |
| SCHEMBL29368798 | 0.90 | CASP3 (0.52) | CASP3PIN1KMT2AEPHX2 | |
| SCHEMBL30656017 | 0.90 | CASP3 (0.52) | CASP3PIN1KMT2AEPHX2 | |
| SCHEMBL5706475 | 0.89 | CASP3 (0.47) | CASP3PIN1KMT2AEPHX2 | |
| SCHEMBL14019298 | 0.87 | POLB (0.51) | CASP3PIN1KMT2APOLBCYP3A4 | |
| SCHEMBL31546599 | 0.87 | POLB (0.51) | CASP3PIN1KMT2APOLBCYP3A4 | |
| SCHEMBL3210403 | 0.85 | CASP3 (0.49) | CASP3PIN1KMT2ACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662782-B2 | Melanocortin 1 receptor selective compounds | ACTION PHARMA A/S (DK) | 2010-02-16 | — | — | US | disclosed |
| US-20070027086-A1 | Melanocortin 1 receptor selective compounds | SZARDENINGS MICHAEL | 2007-02-01 | — | — | US | disclosed |
| EP-1075492-B1 | MELANOCORTIN 1 RECEPTOR SELECTIVE COMPOUNDS | ACTION PHARMA AS (DK) | 2006-07-19 | — | — | EP | disclosed |
| US-7008925-B1 | Melanocortin 1 receptor selective compounds | ACTION PHARMA A/S (DK) | 2006-03-07 | — | — | US | disclosed |
| EP-1075492-A1 | MELANOCORTIN 1 RECEPTOR SELECTIVE COMPOUNDS | Wa Pharm AB (SE) | 2001-02-14 | — | — | EP | disclosed |
| WO-1999057148-A1 | MELANOCORTIN 1 RECEPTOR SELECTIVE COMPOUNDS | WA PHARM AB (SE) | 1999-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027086-A1 | Melanocortin 1 receptor selective compounds | MC5R, MC1R, MC2R | CASP3 4875/4885PIN1 3095/4885KMT2A 2343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.