Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118787 | 0.77 | BRD4 (0.50) | BRD4HTT | |
| SCHEMBL1885143 | 0.76 | ALDH1A1 (0.46) | ERN1ALDH1A1IMPDH2KDM4EBRD4 | |
| SCHEMBL19785508 | 0.76 | ERN1 (0.35) | ERN1ALDH1A1KDM4EPRKDCLMNA | |
| SCHEMBL174142 | 0.74 | BRD4 (0.35) | ALDH1A1KDM4EBRD4HTT | |
| SCHEMBL5393454 | 0.72 | — | — | |
| SCHEMBL106685 | 0.71 | AURKA (0.49) | BRD4HTT | |
| SCHEMBL16651268 | 0.71 | BRD4 (0.39) | BRD4HTT | |
| SCHEMBL1856897 | 0.71 | HDAC8 (0.35) | ALDH1A1KDM4EBRD4HTT | |
| SCHEMBL16339860 | 0.71 | HTT (0.33) | BRD4HTT | |
| SCHEMBL16478319 | 0.71 | MAP2K1 (0.41) | BRD4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514708-A | Pyridine-amide compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-08-01 | — | — | CN | disclosed |