Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 12/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14811661 | 0.80 | AHR (0.81) | AHR | |
| SCHEMBL30601215 | 0.76 | AHR (1.00) | AHRRAB9ANPC1PIK3CG | |
| SCHEMBL14811152 | 0.74 | AHR (0.65) | AHRCYP11B2CYP11B1MAPTALDH1A1 | |
| SCHEMBL30601220 | 0.73 | AHR (1.00) | AHRRAB9ANPC1CYP11B2MAPT | |
| SCHEMBL9903850 | 0.72 | AHR (0.58) | AHRRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL12825740 | 0.71 | AHR (0.61) | AHRRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL30601190 | 0.71 | AHR (1.00) | AHRRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL30601186 | 0.71 | AHR (1.00) | AHRRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL30601227 | 0.71 | AHR (1.00) | AHRRAB9ANPC1CYP11B2CYP11B1 | |
| SCHEMBL30601235 | 0.70 | AHR (0.53) | AHRRAB9ANPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514801-B | 2-Phenyl- [1,2,4] triazolo [1,5-a ] pyridine compound, nitrogen oxide thereof and application thereof | 四川大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-116514801-A | 2-phenyl- [1,2,4] triazolo [1,5-a ] pyridine compound, nitrogen oxide thereof and application thereof | 四川大学 | 2023-08-01 | — | — | CN | disclosed |