Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 11/20 | 0.53 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601178 | 0.80 | AHR (0.60) | AHRLMNAMEN1NPC1ALDH1A1 | |
| SCHEMBL30601198 | 0.76 | AHR (0.70) | AHRLMNAMEN1NPC1ALDH1A1 | |
| SCHEMBL204357 | 0.73 | S100A4 (0.61) | S100A4TRPV1ALDH1A1MAPTMAPK1 | |
| SCHEMBL30601225 | 0.70 | AHR (1.00) | AHRMEN1NPC1ALDH1A1POLB | |
| SCHEMBL30601220 | 0.69 | AHR (1.00) | AHRMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL30601215 | 0.69 | AHR (1.00) | AHRNPC1RAB9A | |
| SCHEMBL14906924 | 0.68 | S100A4 (0.56) | S100A4TRPV1MEN1NPC1ALDH1A1 | |
| SCHEMBL5321726 | 0.67 | S100A4 (0.54) | AHRS100A4TRPV1LMNAMEN1 | |
| SCHEMBL11731287 | 0.66 | GABRA1 (0.54) | S100A4TRPV1LMNAMEN1ALDH1A1 | |
| SCHEMBL618586 | 0.65 | AHR (0.60) | AHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514801-B | 2-Phenyl- [1,2,4] triazolo [1,5-a ] pyridine compound, nitrogen oxide thereof and application thereof | 四川大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-116514801-A | 2-phenyl- [1,2,4] triazolo [1,5-a ] pyridine compound, nitrogen oxide thereof and application thereof | 四川大学 | 2023-08-01 | — | — | CN | disclosed |