Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601247 | 0.82 | EPHX2 (0.39) | EPHX2KDM4ETDP1TSHRMAPT | |
| SCHEMBL30601270 | 0.76 | EPHX2 (0.43) | EPHX2KDM4ETDP1TSHRMAPT | |
| SCHEMBL30601236 | 0.73 | MAPT (0.48) | EPHX2KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL31556703 | 0.73 | ADORA2A (0.41) | EPHX2MAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL15908738 | 0.72 | TSHR (0.46) | EPHX2KDM4ETSHRMAPTHSD17B10 | |
| SCHEMBL26246526 | 0.72 | EPHX2 (0.44) | EPHX2KDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL11247916 | 0.71 | TSHR (0.62) | KDM4ETDP1TSHRMAPTHSD17B10 | |
| SCHEMBL28905637 | 0.71 | TSHR (0.40) | EPHX2TSHRHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL5337383 | 0.70 | SMN1; SMN2 (0.48) | EPHX2KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4579114 | 0.69 | PKM (0.49) | KDM4ETDP1TSHRMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514816-A | Pyrimidinone pyrrole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-08-01 | — | — | CN | disclosed |