SCHEMBL4579114

SCHEMBL4579114

CCOC(=O)Cc1ccccc1CC#N

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.49
CYP4F2 P78329 2/20 0.46
CYP4A11 Q02928 2/20 0.46
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
TDP1 Q9NUW8 1/20 0.42
POLB P06746 1/20 0.42
NLRP3 Q96P20 1/20 0.42
TBXAS1 P24557 1/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68340 0.86 PKM (0.60) PKMCYP4F2CYP4A11ALDH1A1MEN1
SCHEMBL11545353 0.84 CYP4F2 (0.68) CYP4F2CYP4A11ALDH1A1KDM4EKMT2A
SCHEMBL31424953 0.83 PKM (0.57) PKMCYP4F2CYP4A11ALDH1A1MEN1
SCHEMBL6878047 0.83 PKM (0.57) PKMCYP4F2CYP4A11ALDH1A1MEN1
SCHEMBL31424955 0.83 PKM (0.57) PKMCYP4F2CYP4A11ALDH1A1MEN1
SCHEMBL7219075 0.81 NLRP3 (0.55) PKMCYP4F2CYP4A11ALDH1A1KDM4E
SCHEMBL28670364 0.80 PKM (0.54) PKMCYP4F2CYP4A11MEN1KMT2A
SCHEMBL28362403 0.80 PKM (0.54) PKMCYP4F2CYP4A11ALDH1A1KDM4E
SCHEMBL1995793 0.79 PKM (0.38) PKMCYP4F2CYP4A11ALDH1A1KDM4E
SCHEMBL4671445 0.78 PKM (0.53) PKMCYP4F2CYP4A11ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7414146-B2 Imaging element containing a blocked photographically useful compound CARESTREAM HEALTH, INC. (US) 2008-08-19 US disclosed
EP-1315035-B1 Core/shell silver donors for photothermographic systems comprising an oxidatively less reactive shell EASTMAN KODAK CO (US) 2007-03-28 EP disclosed
EP-1380890-B1 High speed thermally developable imaging materials and methods of using the same EASTMAN KODAK CO (US) 2007-01-17 EP disclosed
US-7157219-B2 Photothermographic materials containing silver halide sensitized with combination of compounds EASTMAN KODAK COMPANY (US) 2007-01-02 US disclosed
US-7157214-B2 High-speed thermally developable imaging materials EASTMAN KODAK COMPANY (US) 2007-01-02 US disclosed
US-7112398-B2 Imaging element containing a blocked photographically useful compound EASTMAN KODAK COMPANY (US) 2006-09-26 US disclosed
US-7094524-B2 Thermally development imaging materials having backside stabilizers EASTMAN KODAK COMPANY (US) 2006-08-22 US disclosed
US-7087366-B2 Method for chemical sensitization of silver halide for photothermographic use EASTMAN KODAK COMPANY (US) 2006-08-08 US disclosed
EP-1680710-A1 THERMALLY DEVELOPABLE IMAGING MATERIALS WITH BARRIER LAYER EASTMAN KODAK COMPANY (US) 2006-07-19 EP disclosed
EP-1341033-B1 High speed photothermographic materials containing selenium compounds and methods of using same EASTMAN KODAK CO (US) 2006-06-21 EP disclosed
EP-0639791-A2 Photothermographic elements containing photographically useful compounds with silyl blocking groups MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-22 EP disclosed
US-5382504-A Negative photographic element MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-01-17 US disclosed
US-5380644-A Fluorinated acrylic terpolymer surfactant for coating MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-01-10 US disclosed
US-5370988-A A silver halide emulsions consisting of a reducible silver compound, reducing agents, a binder and a substituted hydroxyphenyl compound; shelf life, stability, high density images, sharpness MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-12-06 US disclosed
US-5369000-A Bromoalkyl sulfone antifogging agents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-11-29 US disclosed
WO-1994025900-A1 PHOTOTHERMOGRAPHIC ELEMENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-11-10 WO disclosed
EP-0622666-A1 Post-processing stabilizers for photothermographic articles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-11-02 EP disclosed
US-5358843-A Deblocking with fluoride ions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-10-25 US disclosed
US-5350669-A Silver-carboxylate/1,2-diazine compounds as silver sources in photothermographic and thermographic elements MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-09-27 US disclosed
EP-0599463-A2 High speed, dry processed printing plate construction MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-01 EP disclosed