Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362265 | 0.95 | P2RX7 (0.61) | P2RX7AHRKMT2AMEN1CES1 | |
| SCHEMBL22288352 | 0.95 | P2RX7 (0.61) | P2RX7AHRKMT2AMEN1CES1 | |
| Hydrochloric Acid SCHEMBL30601969 | 0.93 | P2RX7 (0.59) | P2RX7AHRKMT2AMEN1CES1 | |
| Sulfuric Acid SCHEMBL30601991 | 0.89 | P2RX7 (0.54) | P2RX7AHRKMT2AMEN1CES1 | |
| SCHEMBL30601973 | 0.89 | P2RX7 (0.54) | P2RX7AHRKMT2AMEN1CES1 | |
| SCHEMBL1403853 | 0.83 | P2RX7 (0.67) | P2RX7AHRKMT2AMEN1CES1 | |
| SCHEMBL4040893 | 0.74 | P2RX7 (0.65) | P2RX7AHRKMT2AMEN1CES1 | |
| SCHEMBL1412900 | 0.73 | P2RX7 (0.69) | P2RX7AHRKMT2AMEN1CES1 | |
| SCHEMBL14574955 | 0.73 | ALDH1A1 (0.55) | KMT2ACES1 | |
| Hydrochloric Acid SCHEMBL28798673 | 0.73 | P2RX7 (0.62) | P2RX7AHRKMT2AMEN1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165574-A1 | COMPOUND USED AS TYK2 INHIBITOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 上海致根医药科技有限公司 | 2023-09-07 | — | — | WO | disclosed |