Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5729965 | 0.98 | DRD2 (0.62) | DRD2OPRM1HTR2AOPRL1OPRK1 | |
| Ethane SCHEMBL11603328 | 0.96 | DRD2 (0.60) | DRD2OPRM1HTR2AOPRL1OPRK1 | |
| SCHEMBL16565576 | 0.92 | DRD2 (0.56) | DRD2OPRM1HTR2AOPRL1OPRK1 | |
| SCHEMBL3900447 | 0.88 | DRD2 (0.61) | DRD2OPRM1HTR2AOPRL1OPRK1 | |
| SCHEMBL8729443 | 0.87 | DRD2 (0.51) | DRD2OPRM1HTR2AOPRL1OPRK1 | |
| SCHEMBL1205790 | 0.87 | HTR2A (0.59) | DRD2OPRM1HTR2AOPRL1OPRK1 | |
| SCHEMBL15093670 | 0.87 | HTR2A (0.59) | DRD2OPRM1HTR2AOPRL1OPRK1 | |
| SCHEMBL15093944 | 0.87 | HTR2A (0.59) | DRD2OPRM1HTR2AOPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL3545524 | 0.85 | HTR2A (0.57) | DRD2OPRM1HTR2AOPRL1OPRK1 | |
| SCHEMBL3891047 | 0.83 | DRD2 (0.56) | DRD2OPRM1OPRL1OPRK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2225 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120035580-A | Novel piperazinyl sulfonamides and their use as neuroprotective and/or neurorestorative agents | 基因密码公司 | 2025-05-23 | — | — | CN | claimed |
| CN-119325330-A | Solar cell and preparation method thereof | 天合光能股份有限公司 | 2025-01-17 | — | — | CN | claimed |
| WO-2024125346-A1 | PREPARATION OF DEUTERATED 4-PHENYLPIPERIDINE-4-OL COMPOUND AND USE THEREOF | 南昌双天使生物科技开发有限公司 | 2024-06-20 | — | — | WO | claimed |
| CN-117447388-B | Preparation and application of deuterated 4-phenylpiperidine-4-alcohol compound | 南昌双天使生物科技开发有限公司 | 2024-05-10 | — | — | CN | claimed |
| WO-2024079351-A1 | NOVEL PIPERAZINE-BASED SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | GENECODE (EE) | 2024-04-18 | — | — | WO | claimed |
| CN-117447388-A | Preparation and application of deuterated 4-phenylpiperidine-4-alcohol compound | 南昌双天使生物科技开发有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-114349922-B | Flexible dual-cured resin composition and preparation method of molded body thereof | 浙江华峰新材料有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-114349922-A | Flexible dual-curing resin composition and preparation method of forming body thereof | 浙江华峰新材料有限公司 | 2022-04-15 | — | — | CN | claimed |
| US-9598361-B1 | Amino substituted acetamide derivative | KING SAUD UNIVERSITY (SA) | 2017-03-21 | — | — | US | claimed |
| CN-102388044-A | Heterocyclic inhibitors of histamine receptors for the treatment of diseases | KALYPSYS INC | 2012-03-21 | — | — | CN | claimed |
| EP-0178946-A2 | 1-(Aminoalkyl)-alpha, alpha-diaryl pyrrolidine-piperidine- and homopiperidine- acetamides and acetonitriles | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-04-23 | — | — | EP | claimed |
| US-4558155-A | N-(Aryloxyalkyl)-N'-(aminoalkyl)thioureas | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-12-10 | — | — | US | claimed |
| EP-0160436-A2 | N-[(Amino)Alkyl]-1-pyrrolidine, 1-piperidine and 1-homopiperidinecarboxamides (and thiocarboxamides) with sulphur linked substitution in the 2, 3 or 4-position | A.H. ROBINS COMPANY, INCORPORATED (US) | 1985-11-06 | — | — | EP | claimed |
| US-4500529-A | ANTIARRHYTHMIA AGENT | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-02-19 | — | — | US | claimed |
| US-4236009-A | Method of preparing 4A-arylhexahydro-1H-2-pyrindines and 4A-aryloctahydroisoquinolines | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | claimed |
| US-4171361-A | HYPOTENSIVE | ELI LILLY AND COMPANY (US) | 1979-10-16 | — | — | US | claimed |
| US-4111703-A | HEAT-SENSITIVE COATING COMPOSITION WITH 4-AROMATIC AND HYDROXY SUBSTITUTED PIPERIDINE DERIVATIVE AND CYCLIC POLYKETO COMPOUND | GRAPHIC CONTROLS CORPORATION (US) | 1978-09-05 | — | — | US | claimed |
| US-4045442-A | ANTIINFLAMMATORY, ANTIDIARRHEA | G. D. SEARLE & CO. (US) | 1977-08-30 | — | — | US | claimed |
| US-4022786-A | PHARMACEUTICALS, CNS STIMULANT | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1977-05-10 | — | — | US | claimed |
| US-4017491-A | 1,1-Diaryl-1H-tetrazole amines | G. D. SEARLE & CO. (US) | 1977-04-12 | — | — | US | claimed |