Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306026 | 0.87 | DRD2 (0.64) | DRD2OPRM1OPRL1OPRK1HTR2A | |
| Hydrochloric Acid SCHEMBL5729965 | 0.85 | DRD2 (0.62) | DRD2OPRM1OPRL1OPRK1HTR2A | |
| Ethane SCHEMBL11603328 | 0.83 | DRD2 (0.60) | DRD2OPRM1OPRL1OPRK1HTR2A | |
| SCHEMBL11815569 | 0.81 | OPRL1 (0.50) | OPRM1OPRL1OPRK1SIGMAR1OPRD1 | |
| SCHEMBL16565576 | 0.80 | DRD2 (0.56) | DRD2OPRM1OPRL1OPRK1HTR2A | |
| SCHEMBL3900447 | 0.77 | DRD2 (0.61) | DRD2OPRM1OPRL1OPRK1HTR2A | |
| SCHEMBL1205790 | 0.76 | HTR2A (0.59) | DRD2OPRM1OPRL1OPRK1HTR2A | |
| SCHEMBL15093670 | 0.76 | HTR2A (0.59) | DRD2OPRM1OPRL1OPRK1HTR2A | |
| SCHEMBL15093944 | 0.76 | HTR2A (0.59) | DRD2OPRM1OPRL1OPRK1HTR2A | |
| Hydrochloric Acid SCHEMBL3545524 | 0.74 | HTR2A (0.57) | DRD2OPRM1OPRL1OPRK1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |