Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.53 |
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602780 | 0.88 | CNR1 (0.44) | CNR2CNR1MAOBAPPPTGER4 | |
| SCHEMBL27800056 | 0.78 | CNR2 (0.80) | CNR2CNR1ACHEALDH1A1PTGER4 | |
| SCHEMBL31038875 | 0.77 | PTK2 (0.59) | MAOBAPPALDH1A1TSHRPTK2 | |
| SCHEMBL31038868 | 0.77 | PTK2 (0.59) | MAOBAPPALDH1A1TSHRPTK2 | |
| SCHEMBL30602797 | 0.75 | CNR2 (0.53) | CNR2CNR1ACHEALDH1A1L3MBTL1 | |
| SCHEMBL2760339 | 0.74 | CNR2 (0.70) | CNR2CNR1ACHEALDH1A1PTGER4 | |
| SCHEMBL2433694 | 0.72 | APP (0.69) | MAOBAPPALDH1A1TSHRMAOA | |
| SCHEMBL30602806 | 0.71 | CNR2 (0.50) | CNR2CNR1ACHEPDE5A | |
| SCHEMBL15010701 | 0.70 | MAPT (0.45) | MAOBAPPMAOA | |
| SCHEMBL28170887 | 0.70 | CNR2 (0.66) | CNR2CNR1ACHEALDH1A1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095828-A | Indazole compound, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| WO-2023186058-A1 | INDAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2023-10-05 | — | — | WO | disclosed |