Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 6/20 | 0.59 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.48 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31038875 | 1.00 | PTK2 (0.59) | PTK2GRM2SLC9A1ALDH1A1TSHR | |
| SCHEMBL19911522 | 0.83 | GRM2 (0.60) | PTK2GRM2SLC9A1ALDH1A1HTT | |
| SCHEMBL30602781 | 0.77 | CNR2 (0.53) | PTK2ALDH1A1TSHRMAOBAPP | |
| SCHEMBL19911510 | 0.76 | HCAR3 (0.65) | PTK2GRM2SLC9A1ALDH1A1HTT | |
| SCHEMBL2433694 | 0.73 | APP (0.69) | ALDH1A1TSHRLMNAMAOBHTT | |
| SCHEMBL25702660 | 0.72 | APP (0.52) | ALDH1A1TSHRLMNAMAOBHTT | |
| SCHEMBL21991433 | 0.72 | HCAR3 (0.54) | PTK2GRM2SLC9A1ALDH1A1TSHR | |
| SCHEMBL30991739 | 0.72 | APP (0.52) | ALDH1A1TSHRLMNAMAOBHTT | |
| SCHEMBL19911496 | 0.71 | GRM2 (0.66) | PTK2GRM2SLC9A1ALDH1A1HCAR3 | |
| SCHEMBL29248217 | 0.70 | PTK2 (0.48) | PTK2ALDH1A1TSHRLMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4654964-A1 | SULFONE-1H-PYRROLE-2-CARBOXAMIDE INHIBITORS OF SARS-COV-2 NSP14 METHYLTRANSFERASE AND DERIVATIVES THEREOF | The Rockefeller University (US) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024158875-A1 | SULFONE-1H-PYRROLE-2-CARBOXAMIDE INHIBITORS OF SARS-COV-2 NSP14 METHYLTRANSFERASE AND DERIVATIVES THEREOF | THE ROCKEFELLER UNIVERSITY (US) | 2024-08-02 | — | — | WO | disclosed |