⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021086 | 1.00 | — | — | |
| SCHEMBL7016673 | 1.00 | — | — | |
| SCHEMBL8362163 | 0.94 | HPGD (0.42) | — | |
| SCHEMBL30135339 | 0.82 | NOS2 (0.46) | — | |
| SCHEMBL30135380 | 0.82 | NOS2 (0.46) | — | |
| SCHEMBL9328453 | 0.82 | NOS2 (0.46) | — | |
| SCHEMBL14984838 | 0.80 | — | — | |
| SCHEMBL6444441 | 0.78 | — | — | |
| SCHEMBL1625646 | 0.78 | — | — | |
| SCHEMBL7016675 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150581-B1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2020-04-15 | — | — | EP | claimed |
| US-20170190715-A1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2017-07-06 | — | — | US | claimed |
| EP-3150581-A1 | PYRIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2017-04-05 | — | — | EP | claimed |
| US-7687490-B2 | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2010-03-30 | — | — | US | claimed |
| EP-1870412-A1 | 2-THIOETHENYL CARBAPENEM DERIVATIVE | MEIJI SEIKA KAISHA LTD. (JP) | 2007-12-26 | — | — | EP | claimed |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-01-04 | — | — | US | claimed |
| EP-0786457-B1 | AZOLE DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 2002-05-29 | — | — | EP | claimed |
| US-5773442-A | EXHIBIT GPIIB/IIIA RECEPTOR ANTAGONISTIC ACTIVITY; USEFUL FOR THE TREATMENT AND PROPHYLAXIS OF VASCULAR SYSTEM DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-06-30 | — | — | US | claimed |
| EP-0810215-A1 | NOVEL BENZAMIDINE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-03 | — | — | EP | claimed |
| US-10975091-B2 | Pyridine derivative | ASTELLAS PHARMA INC. (JP) | 2021-04-13 | — | — | US | disclosed |
| EP-3150581-B1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2020-04-15 | — | — | EP | disclosed |
| US-20200055868-A1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2020-02-20 | — | — | US | disclosed |
| US-10421762-B2 | Pyridine derivative | ASTELLAS PHARMA INC. (JP) | 2019-09-24 | — | — | US | disclosed |
| US-20180327418-A1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2018-11-15 | — | — | US | disclosed |
| US-5773442-A | EXHIBIT GPIIB/IIIA RECEPTOR ANTAGONISTIC ACTIVITY; USEFUL FOR THE TREATMENT AND PROPHYLAXIS OF VASCULAR SYSTEM DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0810215-A1 | NOVEL BENZAMIDINE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-03 | — | — | EP | disclosed |
| EP-0757050-A1 | Antibacterial penem esters derivatives | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
| EP-0691343-A1 | CEPHALOSPORIN DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-01-10 | — | — | EP | disclosed |
| EP-0544907-A1 | ANTIBACTERIAL PENEM ESTERS DERIVATIVES | SUNTORY LIMITED (JP) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992003442-A1 | ANTIBACTERIAL PENEM ESTERS DERIVATIVES | SUNTORY LIMITED (JP) | 1992-03-05 | — | — | WO | disclosed |