Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.41 |
| ▸ | HTR3B | O95264 | 3/20 | 0.41 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604068 | 0.88 | PLA2G2A (0.55) | PLA2G2ATACR3KDM4EHTR3EHTR3B | |
| SCHEMBL30604090 | 0.87 | TACR3 (0.43) | PLA2G2ATACR3KDM4EHTR3EHTR3B | |
| SCHEMBL30604150 | 0.87 | TACR3 (0.43) | PLA2G2ATACR3KDM4EHTR3EHTR3B | |
| SCHEMBL30604271 | 0.87 | TACR3 (0.43) | PLA2G2ATACR3KDM4EHTR3EHTR3B | |
| SCHEMBL29091050 | 0.87 | TACR3 (0.43) | PLA2G2ATACR3KDM4EHTR3EHTR3B | |
| SCHEMBL30604128 | 0.87 | PLA2G2A (0.44) | PLA2G2ATACR3KDM4EHTR3EHTR3B | |
| SCHEMBL30604157 | 0.87 | PLA2G2A (0.54) | PLA2G2ATACR3KDM4EHTR3EHTR3B | |
| SCHEMBL30604152 | 0.87 | KDM4E (0.51) | PLA2G2ATACR3KDM4EALDH1A1LMNA | |
| SCHEMBL29091034 | 0.85 | KDM4E (0.54) | TACR3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL30604135 | 0.84 | PLA2G2A (0.56) | PLA2G2ATACR3KDM4EHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745291-A | N- (2- (4-cyanothiazolidin-3-yl) -2-oxoethyl) -quinoline-4-carboxamide | 阿斯利康(瑞典)有限公司 | 2023-09-12 | — | — | CN | disclosed |