Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604068 | 0.90 | PLA2G2A (0.55) | KDM4EL3MBTL1ALDH1A1HPGDLMNA | |
| SCHEMBL30604157 | 0.89 | PLA2G2A (0.54) | KDM4EL3MBTL1ALDH1A1HPGDLMNA | |
| SCHEMBL29091034 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL30604147 | 0.87 | PLA2G2A (0.43) | KDM4EL3MBTL1ALDH1A1HPGDLMNA | |
| SCHEMBL30604135 | 0.86 | PLA2G2A (0.56) | KDM4EL3MBTL1ALDH1A1HPGDLMNA | |
| SCHEMBL30604062 | 0.86 | KDM4E (0.53) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL30604108 | 0.85 | NCOA1 (0.48) | KDM4EL3MBTL1ALDH1A1HPGDLMNA | |
| SCHEMBL13576788 | 0.84 | KDM4E (0.55) | KDM4EL3MBTL1ALDH1A1HPGDLMNA | |
| SCHEMBL30604154 | 0.84 | KDM4E (0.51) | KDM4EL3MBTL1ALDH1A1HPGDLMNA | |
| SCHEMBL30604092 | 0.84 | TACR3 (0.47) | KDM4EL3MBTL1ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745291-A | N- (2- (4-cyanothiazolidin-3-yl) -2-oxoethyl) -quinoline-4-carboxamide | 阿斯利康(瑞典)有限公司 | 2023-09-12 | — | — | CN | disclosed |