Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604177 | 0.88 | KDM4E (0.59) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL30604076 | 0.87 | KDM4E (0.44) | KDM4ELMNAPLA2G2A | |
| SCHEMBL30604186 | 0.85 | PLA2G2A (0.53) | KDM4EMAPK1TDP1ALDH1A1LMNA | |
| SCHEMBL30604220 | 0.85 | PLA2G2A (0.53) | KDM4EMAPK1TDP1ALDH1A1LMNA | |
| SCHEMBL30604065 | 0.85 | PLA2G2A (0.53) | KDM4EMAPK1TDP1ALDH1A1LMNA | |
| SCHEMBL30604071 | 0.85 | KDM4E (0.49) | KDM4ELMNAPLA2G2A | |
| SCHEMBL30604178 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL30604152 | 0.84 | KDM4E (0.51) | KDM4EL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL30604151 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL29091020 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745291-A | N- (2- (4-cyanothiazolidin-3-yl) -2-oxoethyl) -quinoline-4-carboxamide | 阿斯利康(瑞典)有限公司 | 2023-09-12 | — | — | CN | disclosed |