Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.66 |
| ▸ | DHODH | Q02127 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13957934 | 0.85 | KDM4E (0.63) | TACR3DHODHMEN1KMT2AKDM4E | |
| SCHEMBL30102549 | 0.85 | KDM4E (0.63) | TACR3DHODHMEN1KMT2AKDM4E | |
| SCHEMBL14518623 | 0.85 | MEN1 (0.72) | DHODHMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30604083 | 0.83 | TACR3 (0.57) | TACR3DHODHMEN1KMT2AKDM4E | |
| Bromide SCHEMBL4383984 | 0.82 | MEN1 (0.69) | DHODHMEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4562712 | 0.82 | MEN1 (0.69) | TACR3DHODHMEN1KMT2AKDM4E | |
| SCHEMBL2576382 | 0.81 | KDM4E (0.76) | TACR3DHODHMEN1KMT2AKDM4E | |
| SCHEMBL6448659 | 0.80 | TACR3 (1.00) | TACR3MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL14518625 | 0.80 | MEN1 (0.66) | DHODHMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30690048 | 0.78 | DHODH (0.66) | DHODHMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745291-A | N- (2- (4-cyanothiazolidin-3-yl) -2-oxoethyl) -quinoline-4-carboxamide | 阿斯利康(瑞典)有限公司 | 2023-09-12 | — | — | CN | disclosed |