Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23972286 | 1.00 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL697151 | 0.78 | AKR1C1 (0.48) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL30344677 | 0.76 | SLC6A3 (0.42) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL8747018 | 0.76 | SLC6A3 (0.42) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL31459298 | 0.76 | HDAC4 (0.49) | TSHRCYP3A4KIF11TDP1 | |
| SCHEMBL8112531 | 0.73 | AKR1C1 (0.52) | SLC6A3SLC6A4SLC6A2KIF11TDP1 | |
| SCHEMBL29876796 | 0.72 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL28485903 | 0.72 | SLC6A3 (0.49) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL25155197 | 0.72 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL8106448 | 0.71 | SLC6A3 (0.45) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4142874-B1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | RAQUALIA PHARMA INC (JP) | 2026-04-22 | — | — | EP | disclosed |