Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 6/20 | 0.50 |
| ▸ | SKP1 | P63208 | 6/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 6/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30605678 | 0.86 | CKS1B (0.47) | CKS1BSKP1SKP2GPR84PDE10A | |
| SCHEMBL11679597 | 0.85 | CKS1B (0.53) | CKS1BSKP1SKP2GPR84CNR1 | |
| SCHEMBL22332490 | 0.83 | TDP1 (0.49) | CKS1BSKP1SKP2GPR84ADORA3 | |
| SCHEMBL6326233 | 0.79 | CKS1B (0.44) | CKS1BSKP1SKP2GPR84PDE10A | |
| SCHEMBL5218013 | 0.77 | CKS1B (0.41) | CKS1BSKP1SKP2GPR84PDE10A | |
| SCHEMBL25060778 | 0.77 | CKS1B (0.40) | CKS1BSKP1SKP2GPR84CNR1 | |
| SCHEMBL10385698 | 0.76 | CKS1B (0.47) | CKS1BSKP1SKP2GPR84CNR1 | |
| SCHEMBL3989700 | 0.75 | CKS1B (0.48) | CKS1BSKP1SKP2ADORA3CNR1 | |
| SCHEMBL22332582 | 0.75 | CTSS (0.45) | CKS1BSKP1SKP2CTSKSREBF2 | |
| SCHEMBL20885791 | 0.74 | CHEK1 (0.52) | CNR1MAPTTP53KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745270-A | Process for preparing diphenylpyrazine derivatives | 埃科特莱茵药品有限公司 | 2023-09-12 | — | — | CN | disclosed |