Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 1.00 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.79 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21430778 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| SCHEMBL21412790 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| SCHEMBL13021665 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| SCHEMBL30607236 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| SCHEMBL13074858 | 0.90 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| SCHEMBL20016619 | 0.89 | ROCK2 (0.82) | ROCK2ROCK1MYLK4 | |
| SCHEMBL19886639 | 0.89 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| SCHEMBL22593432 | 0.89 | ROCK2 (0.79) | ROCK2ROCK1MYLK4 | |
| SCHEMBL24336110 | 0.89 | ROCK2 (0.81) | ROCK2ROCK1MYLK4 | |
| SCHEMBL21775058 | 0.89 | ROCK2 (0.81) | ROCK2ROCK1MYLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117050013-A | Mono (acid) salts of 6-aminoisoquinolines and use thereof | 爱瑞制药公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111936139-B | Mono (acid) salts of 6-aminoisoquinolines and use thereof | 爱瑞制药公司 | 2023-10-13 | — | — | CN | disclosed |