SCHEMBL30607275

CC[C@H](C)[C@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CN)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.65

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	3/20	0.62

▸	APLNR	P35414	2/20	0.61

▸	KEAP1	Q14145	1/20	0.60

▸	F2	P00734	4/20	0.57

▸	GLP1R	P43220	6/20	0.57

▸	GCGR	P47871	5/20	0.57

▸	GIPR	P48546	5/20	0.57

▸	CRHR1	P34998	1/20	0.57

▸	CRHR2	Q13324	1/20	0.57

▸	C5AR1	P21730	1/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30495617	0.93	CALCR (0.68)	CALCRAPLNRKEAP1F2GLP1R
SCHEMBL30432255	0.90	CALCR (0.67)	CALCRAPLNRKEAP1F2GLP1R
SCHEMBL29652674	0.90	CALCR (0.73)	CALCRAPLNRF2GLP1RCRHR1
SCHEMBL29389060	0.88	CALCR (0.72)	CALCRAPLNRGLP1RGCGRCRHR1
SCHEMBL31419713	0.88	CALCR (0.73)	CALCRKEAP1GLP1RGCGRGIPR
SCHEMBL29949373	0.88	CALCR (0.70)	CALCRAPLNRKEAP1GLP1RGCGR
SCHEMBL31182945	0.87	CALCR (0.68)	CALCRAPLNRKEAP1F2GLP1R
SCHEMBL30565138	0.87	CALCR (0.68)	CALCRAPLNRKEAP1GLP1RGCGR
SCHEMBL30565140	0.87	CALCR (0.68)	CALCRAPLNRKEAP1GLP1RGCGR
SCHEMBL29446761	0.87	APLNR (0.62)	CALCRAPLNRKEAP1F2GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12383505-B2	Nanoparticle for the remodeling of cancer-associated fibroblasts	UNIVERSITY OF SOUTH CAROLINA (US)	2025-08-12	—	—	US	disclosed
US-20230310331-A1	NANOPARTICLE FOR THE REMODELING OF CANCER-ASSOCIATED FIBROBLASTS	UNIVERSITY OF SOUTH CAROLINA (US)	2023-10-05	—	—	US	disclosed